This graphical abstract for Science illustrates a de novo computational protein design method for epitope-focused immunogens, which were then tested in vivo in primates. Using a cocktail of three computationally designed proteins, Sesterhenn et al. elicit virus neutralizing antibodies in primates.
Publication: De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Fabian Sesterhenn et al. Science
Dr. Thomas Splettstößer
Warschauer Str. 69
10243 Berlin
Germany
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